Skip to main content
. 2016 Mar 18;12(3):e1005853. doi: 10.1371/journal.pgen.1005853

Fig 7. The MERTK gene contains a novel alternative final exon but usage is not genotype-dependent.

Fig 7

(A) Exon junctions in RNA sequencing data were visualised using IGV_2.3.35. Representative junction maps for a low (rs7422195 GG) and high (rs7422195 AA) expressing sample are shown. Each shows the presence of a junction from exon 18 to a putative novel alternative final exon excluding exon 19. (B) RT-PCR analysis of a high and low expressing sample show the presence of this exon only in combination with exon 18 and not exon 19. (C) Exon usage analysis shows overall increased expression of each exon in samples homozygous for the rs7422195 minor (A) allele, but no difference in exon usage following normalisation for overall expression level (D).