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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Hypertension. 2015 Sep 14;66(5):1034–1041. doi: 10.1161/HYPERTENSIONAHA.115.06017

Figure 2.

Figure 2

LSNA, HR, and MAP were increased 1 hr following icv injection of leptin, and these changes were partially reversed by bilateral nanoinjection of SHU9119 into the PVN 30 min later. Top: Representative experiment showing icv leptin + PVN SHU9119 (at arrows). Groups are: middle, icv leptin + PVN SHU9119 (n=5); bottom, icv aCSF + PVN SHU9119 (n=6). *: P<0.05, compared to baseline control values (CON); †: P<0.05 compared to icv aCSF at the same time; ‡: P<0.05, icv leptin + PVN SHU9119 compared to icv leptin + PVN aCSF (Figure 1A).