Table 1. Various Dosing Regimens for VEGF164 Aptamer during 6 Week T cell Colitis Model.
Dose Group | Total Amount | Time between injections | Total Amount Given |
---|---|---|---|
AMD Patient | 0.3 mg | 6 weeks | 0.3 mg |
Low | 40 mg/kg | 2 days | 18 mg |
Medium | 80 mg/kg | 2 days | 36 mg |
High | 160 mg/kg | 2 days | 72 mg |
The amount of the VEGF164 aptamer (Macugen) given in AMD treatment, and the amount given in our low, medium, and high doses per day, the frequency of dosing, and the total dose given over a 6- week period.