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. Author manuscript; available in PMC: 2016 Mar 18.
Published in final edited form as: Inflamm Bowel Dis. 2010 Nov 9;17(7):1501–1512. doi: 10.1002/ibd.21525

Table 1. Various Dosing Regimens for VEGF164 Aptamer during 6 Week T cell Colitis Model.

Dose Group Total Amount Time between injections Total Amount Given
AMD Patient 0.3 mg 6 weeks 0.3 mg
Low 40 mg/kg 2 days 18 mg
Medium 80 mg/kg 2 days 36 mg
High 160 mg/kg 2 days 72 mg

The amount of the VEGF164 aptamer (Macugen) given in AMD treatment, and the amount given in our low, medium, and high doses per day, the frequency of dosing, and the total dose given over a 6- week period.