Table II.

Grade 3 and 4 hematologic and non-hematologic toxicities occurring during any treatment course and deemed possibly, probably, or definitely related to the treatment

	# of events, # of patients (% of patients)
Hematologic toxicities	Grade 3	Grade 4
Anemia	3, 3 (15)	0, 0 (0)
Lymphocyte count decreased	2, 1 (5)	0, 0 (0)
Neutrophil count decreased	6, 5 (25)	1, 1 (5)
Platelet count decreased	2, 2 (10)	0, 0 (0)
White blood cell decreased	5, 3 (15)	2, 2 (10)
	# of events, # of patients (% of patients)
Non-hematologic toxicities	Grade 3	Grade 4
Dyspnea	1, 1 (5)*	0, 0 (0)
Febrile neutropenia	1, 1 (5)	0, 0 (0)
Hypokalemia	1, 1 (5)	0, 0 (0)
Hyponatremia	2, 2 (10)	0, 0 (0)
Pneumonitis	1, 1 (5)*	0, 0 (0)

^*Dyspnea and pneumonitis were observed in the same patient.