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. Author manuscript; available in PMC: 2017 Mar 18.
Published in final edited form as: Circ Res. 2016 Feb 15;118(6):935–943. doi: 10.1161/CIRCRESAHA.115.308269

Figure 5. WD-induced aortic oxidative stress and maladaptive pro-inflammatory cytokines are ameliorated in ECMR−/− female mice.

Figure 5

(A) Western blot for 3-NT, a marker of oxidant stress from accumulation of oxidant peroxynitrite (ONOO−). (B) mRNA expression of Nox2 and p22phox in aortic tissues. (C) Expression of M1/M2 macrophage marker CD86, CD11c, CD206, and IL10. (D) WD ECMR−/− increased M2 macrophage marker IL10 and CD206 mRNA expression in WD fed mice as measured by real-time PCR. n=4 per group. *P<0.01 compared with CD ECMR+/+; # P<0.05 compared with WD ECMR+/+.