Table 4.

Syndemic Conditions by Sexual Risk Outcomes Among Sexually Active Trans Masculine People Who Have Sex with Men in Massachusetts (n=173).

	Sexual Health Indicator 1:						Sexual Health Indicator 2:						Sexual Health Indicator 3:
	3 or More Sexual Partners – Last 6 Months						STI Diagnosis - Lifetime						Unprotected Anal or Vaginal Sex with a Cisgender Male – Last Sex
	No=135		Yes=38		χ2	aOR	No=163		Yes=10		χ2	aOR	No=159		Yes=14		χ2	aOR
	N	%	N	%	(df)	95% CI	N	%	N	%	(df)	95% CI	N	%	N	%	(df)	95% CI
Drank 5 or More Drinks at One Time – Last 3 Months	48	35.6	22	57.9	34.54** (1)	2.18*** 1.54-3.07	67	41.1	3	30.0	0.92 (1)	1.18 0.62-2.27	65	40.9	5	35.7	0.71 (1)	0.85 0.50-1.44
Polydrug Use – 3 or More Drugs	10	7.4	7	18.4	20.30** (1)	2.17** 1.34-3.51	17	10.4	0	0.0	5.78* (1)	---	15	9.4	2	14.3	1.71 (1)	1.53 0.73-3.18
Depression Diagnosis – Lifetime	69	51.1	26	68.4	17.94** (1)	2.02*** 1.34-3.51	86	52.8	9	90.0	26.39*** (1)	7.43*** 2.88-19.15	87	54.7	8	57.1	0.15 (1)	1.00 0.60-1.65
Anxiety Diagnosis – Lifetime	62	45.9	24	63.2	17.61** (1)	1.73** 1.23-2.45	79	48.5	7	70.0	8.74** (1)	1.76* 1.03-3.00	77	48.4	9	64.3	6.47** (1)	1.76* 1.03-3.00
Intimate Partner Violence – Lifetime	53	39.3	18	47.4	5.13* (1)	1.48* 1.06-2.06	64	39.3	7	70.0	18.07*** (1)	3.27** 1.73-6.19	63	39.6	8	57.1	7.92** (1)	1.93* 1.17-3.18
Childhood Abuse (Physical and/or sexual age < 15 years)	67	49.6	19	50.0	0.01 (1)	1.3 0.93-1.82	79	48.5	7	70.0	8.74** (1)	1.80 0.93-3.47	75	47.2	11	78.6	25.38*** (1)	4.37*** 2.40-7.99

^***P-Value = p<0.0001

^**P-Value = p<0.01

^*P-Value = p<0.05

aOR = Adjusted odds ratio. Adjusted for age and survey mode (online vs. in-person). 95% CI = Confidence Intervals

Note: The bivariate association of polydrug use by lifetime STI diagnosis could not be assessed due to low cell count.