Figure 6. The evolutionary history of carnivore ERV-Fc1 includes numerous cross-species transmission events and at least one recombination event.

Maximum likelihood phylogenetic analysis of carnivore ERV-Fc gag nucleotide sequences: sequences from the dog genome are colored in a shade of red, those from the ferret genome are colored in a shade of blue, and the panda consensus gag is colored in green. The feline ERV-Fc consensus gag sequence has been included as an outgroup and is colored black. For sequences from the dog and ferret genomes, the darker colored taxa are ERV-Fc2 sequences (defined based on their association with an ERV-Fc envelope sequence), while the lighter colored taxa are ERV-Fc1 sequences (defined by an association with ERV-W envelope sequence). Lineages where a large portion of the gag sequence has been replaced with heterologous non-coding sequence is denoted by * in the name. Boostrap confidence values of ancestral nodes are depicted by colored spheres. ERV, endogenous retrovirus.

DOI: http://dx.doi.org/10.7554/eLife.12704.022