Skip to main content
. 2016 Jan 29;5:e12572. doi: 10.7554/eLife.12572

Table 6. Effects of mutations on model parameters.

Significance was determined using the likelihood ratio test as described in Table 4. The sign of the change (Δ) caused by the mutation is shown as “+” if the value moved away from 0, “–” if the value moved towards 0. All p-values are shown without correction for multiple comparisons. Blue denotes significance at p<0.05. Red denotes significance at p<0.05 after Bonferroni correction for 27 comparisons.

HYP DEP
HYP A: eat-4(ad572) HYP B: eat-4(ky5) HYP C: glr-1(n2461) DEP A: glr-1::glr-1(A/T) DEP B: nmr-1::glr-1(A/T)
Control Mutant p < Control Mutant p< Control Mutant p< Control Mutant p< Control Mutant p<
dF (s) 4.771 9.564 + 10-87 4.956 8.643 + 10-64 5.181 7.871 + 10-33 4.771 0.940 10-99 5.181 0.742 10-99
dR (s) 2.043 2.821 + 10-7 1.910 2.769 + 10-12 2.018 3.004 + 10-16 2.045 0.875 10-99 2.018 0.709 10-9 9
dX (s) 0.481 1.040 + 0.005 0.529 0.844 + 10-43 0.459 0.727 + 10-39 0.482 0.328 10-49 0.460 0.235 10-99
dY (s) 0.247 0.382 + 10-5 0.238 0.290 + 0.005 0.221 0.164 10-5 0.247 0.097 10-93 0.221 0.079 10-99
dp (s) 0.428 0.982 + 10-99 0.466 0.793 + 10-52 0.409 0.677 + 10-43 0.428 0.286 10-61 0.409 0.204 10-99
pF 0.729 0.839 + 10-27 0.734 0.832 + 10-26 0.755 0.785 + 0.003 0.728 0.410 10-99 0.755 0.407 10-99
pR 0.177 0.062 10-37 0.167 0.079 10-29 0.161 0.135 10-4 0.177 0.389 + 10-99 0.161 0.404 + 10-99
pX 0.073 0.090 + 10-5 0.077 0.081 + 0.3 0.067 0.073 + 0.03 0.073 0.164 + 10-99 0.067 0.151 + 10-99
pY 0.022 0.009 10-13 0.021 0.008 10-25 0.018 0.007 10-27 0.022 0.037 + 10-21 0.018 0.037 + 10-41