Table 1.
Knosp tumor grades, mean endocan IRS, and mean MVD score for CD34/CD105-positive capillaries in 66 pituitary adenomas
| Knosp grade | No. | Mean IRS-TCs | Mean IRS-ECs | MVD | |
|---|---|---|---|---|---|
| CD34 (Mean ± SD) | CD105 (Mean ± SD) | ||||
| 0 | 13 | 4.8 | 1.8 | 44.3 ± 30.1 | 40.4 ± 23.4 |
| 1 | 10 | 4.1 | 4.4 | 46.0 ± 22.2 | 44.7 ± 18.1 |
| 2 | 15 | 6.8 | 4.9 | 50.4 ± 30.1 | 51.6 ± 28.4 |
| 3 | 13 | 9.2 | 4.2 | 60.8 ± 30.6 | 55.3 ± 31.9 |
| 4 | 15 | 10.2 | 4.3 | 48.3 ± 17.9 | 47.6 ± 16.7 |
| Total | 66 | 7.2* | 3.9 | 50.1 ± 26.6 | 48.2 ± 24.4 |
| Pituitary | 5 | 5.2 | 3.0 | 72.1 ± 9.7 | 136.8 ± 35.4 |
TCs tumor cells, ECs endothelial cells
* In 66 pituitary adenomas, tumor cells IRS was significant higher than vascular endothelial cell IRS (P < 0.001)