TABLE 1.
Expression levels of ECM genes up-regulated in d 4 Msx1d/d/Msx2d/d stroma
|
Msx1/Msx2 stroma |
||||
|---|---|---|---|---|
| Gene | Gene name | f/f RPKM | d/d RPKM | FC (Increase) |
| A2m | α-2-mcroglobulin | 2.848 | 43.929 | 15.423 |
| Adamts7 | ADAM metallopeptidase, thrombospondin 1, 7 | 26.539 | 81.880 | 3.085 |
| Col1a1 | Collagen, type I, α 1 | 336.812 | 709.140 | 2.105 |
| Col6a2 | Collagen, type VI, α 2 | 148.398 | 321.316 | 2.165 |
| Col6a3 | Collagen, type VI, α 3 | 79.941 | 240.153 | 3.004 |
| Col6a4 | Collagen, type VI, α 4 | 120.587 | 464.690 | 3.854 |
| Col6a6 | Collagen, type VI, α 6 | 9.437 | 43.891 | 4.651 |
| Crispld2 | Cysteine-rich secretory protein LCCL domain containing 2 | 10.274 | 23.473 | 2.285 |
| Eln | Elastin | 7.697 | 15.481 | 2.011 |
| Fbn2 | Fibrillin 2 | 6.383 | 15.184 | 2.379 |
| Htra1 | HtrA serine peptidase 1 | 60.633 | 120.113 | 1.981 |
| Loxl2 | Lysyl oxidase-like 2 | 47.085 | 119.687 | 2.542 |
| Mfap4 | Microfibrillar-associated protein 4 | 20.411 | 54.503 | 2.670 |
| Ogn | Osteoglycin | 18.341 | 75.456 | 4.114 |
| Smoc2 | SPARC-related modular calcium binding 2 | 11.506 | 34.331 | 2.984 |
| Spon2 | Spondin 2, extracellular matrix protein | 16.654 | 36.795 | 2.209 |
| Tgfb3 | Transforming growth factor, β 3 | 7.145 | 14.178 | 1.984 |
| Thbs1 | Thrombospondin 1 | 35.551 | 81.533 | 2.293 |
| Wnt5a | Wingless-type MMTV integration site family, member 5A | 46.631 | 97.147 | 2.083 |
Up-regulated genes (2-fold) in Msx1d/d/Msx2d/d stroma that contributed to the ECM GO: Cellular Components (19 unique genes).