TABLE 2.
Expression levels of genes associated with uterine receptivity
Luminal epithelium |
Stroma |
||||||
---|---|---|---|---|---|---|---|
Gene | Gene name | f/f RPKM | d/d RPKM | FC | f/f RPKM | d/d RPKM | FC |
Adm | Adrenomedullin | 0.77 | 0.21 | 0.27 | 5.15 | 10.57 | 2.05 |
Areg | Amphiregulin | 44.49 | 54.27 | 1.22 | 0.00 | 0.00 | N/A |
Bmp2 | Bone morphogenetic protein 2 | 0.00 | 0.08 | N/A | 1.76 | 2.41 | 1.37 |
Fkbp4 | FK506 binding protein 4 (a.k.a. FKBP52) | 187.01 | 294.25 | 1.57 | 77.40 | 122.10 | 1.58 |
Hbegf | Heparin-binding EGF-like growth factor | 1.35 | 6.19 | 4.60 | 1.11 | 0.70 | 0.63 |
Hoxa10 | Homeobox A10 | 3.04 | 2.36 | 0.78 | 148.38 | 168.41 | 1.13 |
Hoxa11 | Homeobox A11 | 2.13 | 2.12 | 1.00 | 122.70 | 113.13 | 0.92 |
Ihh | Indian hedgehog | 18.38 | 45.61 | 2.48 | 0.00 | 0.30 | N/A |
Klf5 | Kruppel-like factor 5 | 20.96 | 23.05 | 1.10 | 0.46 | 0.72 | 1.55 |
Lif | Leukemia inhibitory factor | 0.79 | 5.91 | 7.50 | 0.00 | 0.77 | N/A |
Lifr | Leukemia inhibitory factor receptor α | 6.54 | 32.25 | 4.93 | 7.64 | 7.32 | 0.96 |
Lpar3 | Lysophosphatidic acid receptor 3 | 125.95 | 142.86 | 1.13 | 0.22 | 0.37 | 1.66 |
Mki67 | Antigen identified by Ki-67 antibody | 3.90 | 4.15 | 1.06 | 92.51 | 79.91 | 0.86 |
Nog | Noggin | 1.10 | 0.25 | 0.22 | 4.33 | 2.20 | 0.51 |
Pla2g4a | Phospholipase A2, group IVA | 146.97 | 156.38 | 1.06 | 4.55 | 3.23 | 0.71 |
Ptgs1 | Prostaglandin-endoperoxide synthase 1 | 92.84 | 187.58 | 2.02 | 9.14 | 9.63 | 1.05 |
Ptgs2 | Prostaglandin-endoperoxide synthase 2 | 3.10 | 33.26 | 10.72 | 0.13 | 0.04 | 0.33 |
Sgk1 | Serum/glucocorticoid regulated kinase 1 | 52.25 | 142.06 | 2.72 | 8.20 | 8.13 | 0.99 |
Smo | Smoothened | 3.39 | 6.33 | 1.86 | 35.48 | 52.09 | 1.47 |
Wnt5a | Wingless-type MMTV int. site fam mem 5A | 53.38 | 94.40 | 1.77 | 46.63 | 97.15 | 2.08 |
Wnt7a | Wingless-type MMTV int. site fam mem 7A | 20.16 | 40.91 | 2.03 | 0.00 | 0.00 | N/A |
Compilation of genes associated with uterine receptivity or embryo implantation. Expression levels with FC >2.0 are underlined. An expanded list is presented in Supplemental Table S1.