TABLE 2.
q values (adjusted P values to correct for multiple comparison testing) for offspring diet and maternal diet effect in an initial screen of candidate gene expression
| Gene | Offspring effect | Maternal effect |
|---|---|---|
| Ppia | 0.97 | 0.93 |
| Ogg1 | 0.97 | 0.29 |
| MnSOD | 0.97 | 0.09 |
| CuZnSOD | 0.74 | 0.06 |
| Ccs | 0.57 | 0.09 |
| ECSOD | 0.21 | 0.42 |
| Catalase | 0.19 | 0.99 |
| Nrf2 | 0.68 | 0.06 |
| Gpx1 | 0.41 | 0.78 |
| Gpx4 | 0.74 | <0.01 |
| GR | 0.31 | 0.43 |
| Hmox1 | 0.31 | 0.09 |
| Prdx1 | 0.68 | 0.49 |
| Prdx3 | 0.37 | 0.10 |
| Txnd1 | 0.60 | 0.21 |
| Xo | 0.31 | 0.42 |
| Nox4 | 0.70 | 0.12 |
| Alox12 | 0.41 | 0.06 |
| Cox2 | 0.43 | 0.31 |
| NF-kb | 0.93 | 0.09 |
| IL6 | 0.83 | 0.19 |
| IL1b | 0.16 | 0.31 |
| TnF-α | 0.19 | 0.10 |
| Tfam | 0.41 | 0.09 |
| Pgc-1α | 0.19 | 0.86 |
| Prc | 0.97 | 0.46 |
| p53 | 0.41 | 0.19 |
| p21 | 0.19 | <0.01 |
| p16INK | 0.88 | 0.70 |
| Casp3 | 0.60 | 0.29 |
| Col1A1 | 0.39 | 0.31 |
ECSOD, extracellular superoxide dismutase; Gr, glutathione reductase; Gpx1, glutathione peroxidase 1; Gpx4, glutathione peroxidase 4; Hmox1, hemoxygenase 1; IL6, interleukin 6; IL1-β, interleukin-1 β; Nox4, NADPH oxidase 3; Ogg1, oxoguanine glycosylase 1; Ppia, peptidylprolyl isomerase A (cyclophilin A); Prdx1, peroxiredoxin 1; Prdx3, peroxiredoxin 3; p16INK, cyclin dependent kinase inhibitor 2A; TNF-α, tumor necrosis factor α; Txnrd1, thioredoxin; reductase 1; Xo, xanthine oxidase.