Table 1.
The baseline clinical characteristics before and after the publication of 2013G
| Characteristics | Total (n=5320) | Prior to guideline (n=1871) | After guideline (n=3449) | χ2 or t | P |
|---|---|---|---|---|---|
| Age (years) | 57.18 ± 10.59 | 56.60 ± 10.51 | 57.50 ± 10.63* | 2.960 | 0.0042 |
| Men | 2756 (51.97) | 1018 (54.38) | 1747 (50.65)* | 6.612 | 0.0096 |
| Diabetes mellitus | 889 (16.71) | 296 (15.81) | 593 (17.19) | 1.562 | 0.9981 |
| Hypertension | 2626 (49.36) | 924 (49.36) | 1702 (49.35) | 0.0005 | 0.9981 |
| Hyperlipidemia | 1899 (35.70) | 709 (37.87) | 1190 (34.50)† | 5.856 | 0.0149 |
| Smoking | 1418 (26.65) | 531 (28.37) | 887 (25.72)† | 4.223 | 0.0389 |
| Family history of CAD | 1139 (21.41) | 410 (21.90) | 729 (21.14) | 0.372 | 0.5322 |
| Symptom | |||||
| Asymptomatic patient | 964 (18.12) | 299 (15.97) | 665 (19.28)* | 7.301 | 0.0069 |
| Nonanginal chest pain | 809 (15.21) | 280 (14.95) | 529 (15.34) | ||
| Atypical angina | 2288 (43.01) | 838 (44.76) | 1450 (42.04) | ||
| Typical angina | 1259 (23.66) | 454 (24.25) | 805 (23.34) | ||
| Pretest probability§ | |||||
| <15 | 839 (15.77) | 266 (14.21) | 573 (16.61) | 0.226 | 0.6344 |
| 15≤, <50 | 3161 (59.42) | 1155 (61.73) | 2006 (58.16) | ||
| 50≤, <85 | 1238 (23.27) | 425 (22.72) | 813 (23.57) | ||
| ≥85 | 82 (1.54) | 25 (1.34) | 57 (1.65) | ||
| EF ≥50% | 5130 (96.43) | 1728 (95.19) | 3348 (97.07)‡ | 11.846 | 0.0008 |
| Appropriate stress tests | 222 (4.17) | 49 (2.62) | 173 (5.02)‡ | 16.866 | <0.0001 |
| Outpatient | 4154 (78.08) | 1453 (77.62) | 2701 (78.31) | 0.298 | 0.6062 |
| Appropriate CCTA | 3265 (61.37) | 1145 (61.16) | 2120 (61.46) | 0.034 | 0.8701 |
Values are presented as mean ± SD or n (%). *P<0.01; †P<0.05; ‡P<0.001; §Pretest probability for each patient was calculated using Updated Diamond-Forrester method; CAD: Coronary artery disease; EF: Ejection fraction; CCTA: Coronary computed tomographic angiography; SD: Standard deviation.