Table 3.
mtDNA variants in the reported Chinese Han family
| Gene | Position | Replacement | Previously reported | Frequency | P | |
|---|---|---|---|---|---|---|
| Case group | Control group | |||||
| ND1 | 3970 | C to T | Yes | 1 | 1 | NS |
| 3915 | G to A | Yes | 2 | 0 | NS | |
| 4248 | T to C | Yes | 1 | 0 | NS | |
| tRNAMet | 4435 | A to G | Yes | 3 | 1 | NS |
| tRNALys | 8363 | G to T | Yes | 1 | 0 | NS |
| ATP8 | 8414 | C to T | Yes | 4 | 3 | NS |
| ATP6 | 8793 | T to C | Yes | 1 | 0 | NS |
| ATP6 | 8701 | A to G | Yes | 7 | 1 | 0.005 |
NS: Nonsignificant using Fisher’s exact test. A8701G in ATP6 gene (threonine to alanine) was statistically different after adjusting age, gender, and body surface area (Fisher’s exact test P = 0.005). mtDNA: Mitochondrial DNA.