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. Author manuscript; available in PMC: 2016 Aug 16.
Published in final edited form as: Anal Chem. 2016 Jan 28;88(4):2140–2148. doi: 10.1021/acs.analchem.5b03696

Figure 3.

Figure 3

Raman spectroscopy detects WATi in mammary tissue from a mouse model of post-menopausal diet-induced obesity with high accuracy. (A) Average body weights of ovariectomized LFD (noninflamed) and ovariectomized HFD (inflamed) female mice (n = 10/group), and (B) average number of CLS/cm2 in each group of mice. (In panels (A) and (B), the asterisk (*) denotes P < 0.001.) (C) Raman spectra from inflamed (red, HFD) and noninflamed (blue, LFD) mammary WAT. (D) PC5, which is a diagnostic principal component (PC), contains Raman peaks at 1264 and 1652 cm−1, which are also found to be diagnostic in other datasets (see arrowed features).