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Consort chart. Surgery and EOR prior to study entry in the DIRECTOR trial. Arm A (1 wk on [120 mg/m2 per day]/1 wk off TMZ); arm B (3 wk on [80 mg/m2 per day]/1 wk off TMZ). Black: patients who did not undergo surgery; white: patients with CRET; light gray: patients with incomplete resection.
