Table 6.
Generalized Estimating Equation Analysis of Changes in Specific Symptoms After Adjusting to Baseline Data (n = 84)
| Dependent variable | Independent variable | Estimate | Error | Chi-square | p-Value |
|---|---|---|---|---|---|
| EORTC QLQ-C30 Pain | |||||
| Combined treatment × T5a | −5.53 | 6.12 | 0.816 | 0.366 | |
| Combined treatment × T4 | −4.42 | 5.92 | 0.559 | 0.455 | |
| Combined treatment × T3 | 6.63 | 5.59 | 1.406 | 0.236 | |
| Combined treatment × T2 | 5.38 | 5.90 | 0.833 | 0.362 | |
| EORTC QLQ-C30 | |||||
| Dyspnea | Combined treatment × T5 | 6.76 | 7.56 | 0.800 | 0.371 |
| Combined treatment × T4 | 15.70 | 6.69 | 5.541 | 0.019 | |
| Combined treatment × T3 | 3.17 | 6.70 | 0.225 | 0.635 | |
| Combined treatment × T2 | 7.58 | 6.84 | 1.231 | 0.267 | |
| EORTC QLQ-LC13 | |||||
| Dyspnea | Combined treatment × T5 | 2.84 | 5.68 | 0.248 | 0.618 |
| Combined treatment × T4 | 12.93 | 5.25 | 6.080 | 0.014 | |
| Combined treatment × T3 | 4.05 | 5.24 | 0.599 | 0.439 | |
| Combined treatment × T2 | 2.86 | 4.26 | 0.360 | 0.548 | |
a
Reference group = Western chemotherapy at T1.
T2, the first month after starting treatment; T3, the third month after starting treatment; T4, the sixth month after starting treatment; T5, the 12th month after starting treatment, all as representative variables.