. Author manuscript; available in PMC: 2017 Apr 1.

Published in final edited form as: J Immunol. 2016 Feb 24;196(7):3043–3053. doi: 10.4049/jimmunol.1502056

Table IV.

Trans-genes associated with 25 T1D SNPs with minimum FDR P < 0.001.

ID	T1D SNPs (Effect allele)	Gene	EBV-B Basal	EBV-B PMA	CD4+	CD8+
5	rs1534422 (C)	ST6GAL1	↓^****	ns	ns	ns
10	rs1990760 (T)	LOC643997	↓^***	↓^**	ns	ns
11	rs11571291 (T)	TMUB2	ns	↓^***	ns	ns
13	rs11711054 (C)	GRAMD1B	ns	ns	↑^***	ns
19	rs10499194 (C)	TUBB6	↓^***	↓^***	ns	ns
21	rs7804356 (T)	POLA2	ns	↑^***	ns	ns
		RRP15	ns	↓^***	ns	ns
		SEC61G	ns	↓^***	ns	ns
		SLC39A8	↑^***	↑^**	ns	ns
		TYMS	ns	↑^***	ns	ns
23	rs7020673 (C)	FHL3	ns	↓^***	ns	ns
23	rs7020673 (C)	PLCB2	ns	↑^***	ns	ns
24	rs12251307 (C)	DERA	ns	↑^***	ns	ns
25	rs947474 (C)	MEIS2	↑^***	↑^*	ns	ns
28	rs3842727 (T)	CD276	ns	↓^***	ns	ns
28	rs3842727 (T)	ID2	↑^*	↑^****	ns	ns
30	rs705704 (T)	IP6K2	↑^****	↑^****	↑^****	↑^****
		LOC389386	ns	ns	↑^****	↑^****
		LOC728873	↑^****	ns	ns	ns
		LOC92659	↑^*	↑^*	↑^****	↑^****
		MIR130A	↑^****	↑^****	↑^****	↑^****
		MIR1471	↑^*	↑^*	↑^***	↑^****
33	rs1265565 (T)	ZMYM5	ns	ns	↓^***	ns
34	rs17696736 (C)	IRF8	↑^**	↑^***	ns	ns
34	rs17696736 (C)	NCOA7	↑^*	↑^****	ns	ns
35	rs9585056 (C)	AHCTF1	ns	↓^***	ns	ns
39	rs12908309 (C)	FAHD1	↓^*	↓^****	ns	ns
39	rs12908309 (C)	RNF13	↓^***	ns	ns	ns
40	rs3825932 (C)	PCK2	ns	↑^***	ns	ns
41	rs416603 (T)	SORL1	ns	↑^***	ns	ns
45	rs2290400 (T)	TEX9	↓^*	↓^****	ns	ns
46	rs7221109 (C)	USP14	ns	↑^***	ns	ns
47	rs1893217 (C)	MCM3AP	ns	↓^***	ns	ns
48	rs763361 (T)	P2RY11	↓^*	↓^****	ns	ns
49	rs2304256 (C)	ZNF280D	↑^***	ns	ns	ns
50	rs425105 (T)	CCL5	↑^**	↑^***	ns	ns
51	rs679574 (C)	EIF5A	↓^*	↑^***	ns	ns
53	rs876498 (T)	CAT	ns	↓^***	ns	ns

ID: T1D loci identifiers as in Table I.

Following notations are used: FDR: **** P < 0.0001, *** P < 0.001, ** P < 0.01, * P < 0.05, ns – not significant, ↓ risk allele reduces expression, ↑ risk allele increases expression. T1D SNPs highlighted also showed strong cis-regulatory effects at FDR P < 0.001.