Table VII.
Significant enrichment terms found using DAVID bioinformatics resource.
| ID | T1D SNP | Enrichment Type | Enriched Term | FDR P |
|---|---|---|---|---|
| 2 | rs2476601 | GOterm BP | Antigen processing and presentation of peptide antigen via MHC class I | 0.017 |
| 10 | rs1990760 | PIR Keywords | Acetylation | 0.00065 |
| 15 | rs17388568 | PIR Keywords | Phosphoprotein | 0.025 |
| 22 | rs10272724 | PIR Keywords | Cytoplasm | 0.032 |
| PIR Keywords | Phosphoprotein | 0.047 | ||
| 29 | rs10466829 | PIR Keywords | Lectin | 0.002 |
| GOterm MF | Sugar binding | 0.0096 | ||
| PIR Keywords | Signal-anchor | 0.041 | ||
| GOterm MF | Carbohydrate binding | 0.045 | ||
| 33 | rs3184504 | Interpro | HIN-200/IF120x | 0.0031 |
| 34 | rs17696736 | GOterm BP | Response to virus | 0.00049 |
| PIR Keywords | Antiviral defence | 0.0058 | ||
| 41 | rs416603 | Biocarta | IL-10 Anti-inflammatory Signalling Pathway | 0.0021 |
| KEGG Pathway | Intestinal immune network for IgA production | 0.034 | ||
| 42 | rs9924471 | PIR Keywords | Nucleus | 0.0069 |
| 51 | rs679574 | Smart | IGc1 | 0.0031 |
| KEGG Pathway | Antigen processing and presentation | 0.0088 | ||
| KEGG Pathway | Viral myocarditis | 0.011 | ||
| Interpro | Immunoglobulin/major histocompatibility complex, conserved site | 0.017 | ||
| KEGG Pathway | Graft-versus-host disease | 0.021 | ||
| KEGG Pathway | Allograft rejection | 0.024 |
ID: T1D loci identifiers as in Table I.
PIR: Protein Information Resource, GO: Gene Ontology, BP: Biological process, MF: Molecular Function