Table 3.
Graft quality and unadjusted graft outcomes of organ offers, stratified by adjusted center acceptance and offer acceptance versus decline for first-ranked patients*
| Center acceptance rate category† |
Organ disposition | DRI, median (IQR) | Unadjusted graft survival | ||
|---|---|---|---|---|---|
| 1-year | 3-year | 5-year | |||
| ≥50% | Accepted; transplanted into first-ranked patient | 1.29 (1.09–1.56) | 88.5 (86.1–90.5) | 78.9 (75.7–81.7) | 72.6 (68.9–76.1) |
| Declined; transplanted into lower-ranked patient | 1.42 (1.16–1.70) | 90.1 (87.1–92.4) | 79.8 (75.5–83.4) | 72.6 (67.1–77.3) | |
| 40–49.9% | Accepted; transplanted into first-ranked patient | 1.31 (1.12–1.59) | 88.0 (86.8–89.1) | 78.8 (77.2–80.3) | 71.9 (69.8–73.8) |
| Declined; transplanted into lower-ranked patient | 1.47 (1.21–1.79) | 88.1 (87.0–89.2) | 78.3 (76.7–79.7) | 70.9 (68.9–72.8) | |
| 30–39.9% | Accepted; transplanted into first-ranked patient | 1.34 (1.15–1.63) | 87.0 (85.7–88.2) | 78.2 (76.5–79.8) | 71.7 (69.5–73.8) |
| Declined; transplanted into lower-ranked patient | 1.50 (1.22–1.84) | 87.8 (86.9–88.7) | 78.1 (76.9–79.3) | 69.8 (68.1–71.4) | |
| <30% | Accepted; transplanted into first-ranked patient | 1.37 (1.15–1.68) | 87.4 (85.3–89.2) | 79.3 (76.7–81.7) | 72.2 (68.4–75.5) |
| Declined; transplanted into lower-ranked patient | 1.47 (1.20–1.80) | 87.5 (86.5–88.5) | 77.0 (75.6–78.4) | 69.7 (67.7–71.5) | |
*
Graft quality defined by donor risk index (DRI), as described by Feng et al.20 The DRI accounts for donor variables known to be associated with graft survival, but includes cold ischemic time, which is not determined until after a liver has been transplanted.
†
Center acceptance rate category based on a center’s adjusted organ offer acceptance rate for organs offers to patients ranked first on a match run, described in the Methods section, and Table 2.