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Target sector cores with higher Gleason grade than target cores. a Axial T2-weighted image shows a large lesion (volume 6.09 cm3) in the lateral and anterior left mid-peripheral zone, and b axial diffusion-weighted image shows marked restricted diffusion. c Peri-procedure axial US with target outline and biopsy plan. Both target cores demonstrated Gleason 4 + 3 disease, and background cores from the target sector demonstrated higher grade, Gleason 4 + 5 disease
