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. Author manuscript; available in PMC: 2017 Feb 15.
Published in final edited form as: J Immunol. 2016 Jan 11;196(4):1822–1831. doi: 10.4049/jimmunol.1502206

Figure 1. CD8+ T cells express IL-12, type 1 IFN, and IL-27 receptors throughout Mtb infection.

Figure 1

Expression of the indicated cytokine receptor subunits by sorted CD8+ T cells purified from the lungs of uninfected mice (time 0) and infected mice at the indicated time points. Each point represents the mean ± SEM, of replicates from 3–4 independent infections, each with three pooled mice. Values above 120 (indicated by the dotted line) have a 95% or greater probability of true expression. The receptor subunits shown are: IL-12 receptor (IL-12R; Il12rb1 and Il12rb2), the interferon-α/β receptor (IFNAR; Ifnar1 and Ifnar2), and the IL-27 receptor (IL-27R; Il27ra and Il6st). Receptor subunits displayed in black correspond to the cytokine receptor knockout (KO) mice used in all subsequent figures.