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. 2016 Mar 15;147(4):429–442. doi: 10.1111/imm.12573

Figure 1.

Figure 1

Higher worm burden in Mf+ Litomosoides sigmodontis‐infected BALB/c mice corresponds with an increased lymphocyte number both systemically and in local draining lymph nodes. (a) Wild‐type BALB/c female mice were naturally infected with L. sigmodontis. From day 45 to 120 post infection (p.i.) individual mice were screened for the number of Mf in blood. Symbols represent mean ± SEM of infected mice from six independent infection experiments (n = 20 Mf+ mice). On day 72, L. sigmodontis‐infected BALB/c mice were screened for the presence of peripheral Mf and assessed for changes in worm burden (b), absolute lymphocyte numbers in the spleen (c) and mediastinal lymph nodes (medLN), the draining lymph nodes of the thoracic cavity (d). Symbols represent individual Mf+, Mf– and naive mice from four independent infection experiments (n = 28 Mf+, n = 19 Mf– and n = 15 naive BALB/c mice). Asterisks indicate significant differences (analysis of variance or t‐test) between the groups indicated by the brackets (*P < 0·01, **P < 0·05, ***P < 0·001).