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Estimated values for transplacental transfer parameters obtained in the ex vivo model, mean (range)
| Dcot(l h–1) | KPE (h–1) | Kppl | |
|---|---|---|---|
| Emtricitabine | 0.104 (0.025–0.395) | 1.49* | 3.94 (0.92–9.33) |
| Tenofovir | 0.013 (0.003–0.020) | 0.443 (0.167–1.2) | 7.15 (3.73–1.45) |
Dcot, diffusion parameter; KPE, placental elimination constant; Kppl, coefficient partition.
No variability was estimated.
