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. 2016 Jan 18;594(6):1689–1707. doi: 10.1113/JP271318

Table 3.

Left ventricular epicardial APD90 and CaTD90

Baseline H₂O₂
PCL LV base LV apex LV base LV apex
(ms) APD90 CaTD90 APD90 CaTD90 APD90 CaTD90 APD90 CaTD90
300 NR 112 ± 2 195 ± 4 115 ± 6 190 ± 3 113 ± 3 195 ± 16 116 ± 1 185 ± 15
SHR 128 ± 7***, ††† 178 ± 21 108 ± 4 170 ± 8††† 135 ± 14**, †† 200 ± 2* 107 ± 7 185 ± 3
250 NR 98 ± 9 167 ± 7 96 ± 5 164 ± 8 100 ± 4 143 ± 4 99 ± 12 136 ± 12
SHR 114 ± 19 142 ± 7††† 99 ± 18 141 ± 9, 125 ± 11*, ††† 149 ± 4 104 ± 19 149 ± 20
200 NR 94 ± 8 123 ± 3 93 ± 17 125 ± 2 94 ± 9 125 ± 12 92 ± 10 124 ± 18
SHR 110 ± 9 120 ± 3 99 ± 15 121 ± 7 119 ± 14*, †† 130 ± 7 102 ± 18 124 ± 7
150 NR 88 ± 16 112 ± 9 87 ± 14 114 ± 1 91 ± 6 115 ± 7 88 ± 10 114 ± 2
SHR 100 ± 8 116 ± 6 88 ± 15 115 ± 6 115 ± 7*, ††† 124 ± 6 89 ± 17 120 ± 11

Simultaneous voltage and calcium imaging (four pairs of recordings at the LV base and four pairs at the LV apex per heart, per PCL) were performed for six NR and six SHR hearts before and after perfusion with H2O2. Data are reported as the mean ± SD. Intragroup comparison: *P < 0.05, **P < 0.005, ***P < 0.0005; intergroup comparison: P < 0.05, †† P < 0.005, ††† P < 0.0005; the bootstrap method.