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A, a representative pHi experiment in which the effect of acute hypercapnia on 5 μm forskolin‐stimulated, CFTR‐regulated apical HCO3 − transport was assessed by removal and subsequent re‐addition of apical Cl−. B, ΔpH in response to removal of Cl−. C and D, rate of re‐acidification (C) and HCO3 − flux resulting from re‐addition of apical Cl− (D). Data represent mean ± SEM; n = 6 for each.
