Table 2.

Early Prediction of Pathologic Response (pCR vs. non-pCR)

MRI Metric	pCR	non-pCR		ULR C value
	Mean ± SD	Mean ± SD	P value
V21% Ktrans(TM)	− 64% ± 9%	− 14% ± 41%	.098	0.967
V21% kep(TM)	− 77% ± 9%	− 20% ± 44%	.050	0.957
V21% Ktrans(SSM)	− 71% ± 9%	− 16% ± 50%	.052	0.957
V21% τi	41% ± 26%	− 11% ± 25%	.018	0.946
V2 ve(SSM)	0.78 ± 0.10	0.60 ± 0.14	.073	0.897
V21% ve(TM)	80% ± 60%	35% ± 42%	.026	0.880
V21% ve(SSM)	72% ± 41%	19% ± 28%	.033	0.880
V2 ve(TM)	0.70 ± 0.37	0.29 ± 0.11	.018	0.864
V3 ve(TM)	0.63 ± 0.31	0.32 ± 0.15	.035	0.845
V3 ve(SSM)	0.81 ± 0.11	0.63 ± 0.15	.088	0.845
V1 τi (s)	0.53 ± 0.16	0.81 ± 0.26	.047	0.826
V31% ve(SSM)	80% ± 54%	27% ± 30%	.041	0.810
V21% kep(SSM)	− 77% ± 12%	− 11% ± 94%	.092	0.804
V31% ve(TM)	141% ± 115%	65% ± 85%	.070	0.804
V31% RECIST LD	− 35% ± 21%	− 26% ± 20%	.438	0.673
V21% RECIST LD	− 15% ± 16%	− 10% ± 11%	.320	0.609

ULR: univariate logistic regression; SD: standard deviation; P value: two-sample t test; TM: Tofts model; SSM: Shutter-Speed model.