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Schematic of methods. Four groups of rats were given either chow or HFD (n = 16/group) and measurements were taken of locomotor activity, HFD intake, and neuropeptide expression, and immunofluorescence histochemistry was performed. A additional group of rats was cannulated (n = 18) and given intracerebral injections of either saline or CXCL12, and measurements were taken of locomotor activity, HFD intake, and neuropeptide expression.
