FIGURE 7.

Effects of a high-fat diet and CXCL12 on novelty-induced locomotor activity. (A) The intake of a HFD significantly decreased novelty-induced locomotor activity during 15 min in a novel open field, as measured by ambulatory episodes, ambulatory distance, ambulatory time, and ambulatory counts. N = 16, ^∗p < 0.01; and (B) Intracerebroventricular injection of CXCL12 significantly decreased novelty-induced locomotor activity during 15 min of exposure to the novel open field, as measured by ambulatory episodes, ambulatory distance, ambulatory time, and ambulatory counts. N = 16, ^∗p < 0.01.