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. 2016 Mar 21;4:21. doi: 10.3389/fped.2016.00021

Table 2.

Description of findings on correlation between cumulative fluid balance and clinical outcomes.

Outcome Results
Mortality Significant association in three out of four studies in which mortality was assessed
 Flori p = 0.02
 Willson p < 0.001
 Hu p = 0.079
 Stratified in ≤10 or >10 ml/kg/day p = 0.049
 Valentine p = 0.11
VFDs Significant association in three out of three studies in which VFDs were assessed
 Flori p = 0.02
 Valentine p = 0.01
 Willson p < 0.001
Oxygenation failure Significant association in 1 out of 1 study in which degree of oxygenation failure was assessed
 Willson p = 0.011
Other Willson
 PICU-free days p = 0.14
 Hospital-free days p = 0.06
Randolph
 CFB at extubation associated with duration of weaning p = 0.051