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BH3-mimetic-induced apoptosis in (A) CLL, (B) MOLT-4, (C) H929 and (D) H1299 cells. Cells were incubated with ABT-199 (BCL-2 inhibitor), A-1331852 (BCL-XL inhibitor) and A-1210477 (MCL-1 inhibitor) for 4 h and apoptosis determined. Data represents the mean±s.e.m. of triplicate experiments.
