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Synergy in H1299 cells. H1299 cells (A) were incubated for 1 h with ABT-199 (1 μM), A-1331852 (1 μM) or A-1210477 (10 μM) prior to profiling with either BAD or MS-1 (10 μM) peptide for 2 h and loss of ψm measured. (B) H1299 cells were coincubated with A-1210477 (10 μM) and with A-1331852 for 4 h before apoptosis was measured. Data represents the mean±s.e.m. of triplicate experiments.
