Table 2. Minimal inhibitory concentration (MIC) and antibiotic susceptibility testing (AST) of vancomycin in nine clinical isolates of S. aureus as well as imipenem in ten clinical isolates of E. coli, ten clinical isolates of A. baumannii, and ten clinical isolates of K. pneumoniae determined by SERS-AST (SERS) method and the standard agar dilution (AD) method with inoculum density of 1 × 106 CFU/ml.
Isolate | MIC (μg/ml) and AST |
|||||||
---|---|---|---|---|---|---|---|---|
S. aureus |
E. coli |
A. baumannii |
K. pneumoniae |
|||||
SERS | AD | SERS | AD | SERS | AD | SERS | AD | |
1 | 0.5 (S) | 0.5 (S) | 2 (I) | 4 (R) | 2 (S) | 2 (S) | 2 (I) | 2 (I) |
2 | 1 (S) | 0.5 (S) | 2 (I) | 2 (I) | 2 (S) | 2 (S) | 0.5 (S) | 2 (I) |
3 | 0.5 (S) | 1 (S) | 1 (S) | 2 (I) | 2 (S) | 4 (S) | 1 (S) | 1 (S) |
4 | 1 (S) | 1 (S) | 2 (I) | 4 (R) | 2 (S) | 4 (S) | 1 (S) | 1 (S) |
5 | 2 (S) | 2 (S) | 16 (R) | 32 (R) | 4 (S) | 8 (I) | 0.25 (S) | 0.5 (S) |
6 | 2 (S) | 2 (S) | 1 (S) | 1 (S) | 4 (S) | 8 (I) | 0.125 (S) | 0.5 (S) |
7 | 4 (I) | 4 (I) | 1 (S) | 0.5 (S) | 16 (R) | 16 (R) | 8 (R) | 8 (R) |
8 | 4 (I) | 4 (I) | 0.25 (S) | 1 (S) | 16 (R) | 16 (R) | 4 (R) | 4 (R) |
9 | 8 (I) | 4 (I) | 0.5 (S) | 0.5 (S) | 32 (R) | 32 (R) | 2 (I) | 4 (R) |
10 | — | — | 32 (R) | 32 (R) | 32 (R) | 32 (R) | 4 (R) | 8 (R) |
S: susceptible; I: intermediate; R: resistant.