Table 1. Demographic and clinical characteristics among SORL1 rs3824968 genotypic groups.
| Variables | AA- Homozygotes | AT- Heterozygotes | TT- Homozygotes | P-Value |
|---|---|---|---|---|
| N = 130 | N = 146 | N = 42 | ||
| Age (years) | 53.9 (22.7) | 58.2 (21.6) | 53.9 (21.5) | 0.230 |
| Education (years) | 12.6 (6.7) | 12.2 (5.9) | 13.7 (5.4) | 0.380 |
| Women* | 56 (43.1) | 59 (40.4) | 20 (45.5) | 0.695 |
| Handedness (R/L) | 126/4 | 142/4 | 42/0 | 0.527 |
| APOE-ε4 carriers* | 24 (18.6) | 20 (13.7) | 4 (9.5) | 0.291 |
| Digits Span Forward | 13.8 (2.6) | 13.3 (2.8) | 13.8 (2.2) | 0.296 |
| Digits Span Backward | 7.9 (4.3) | 7.1 (3.8) | 7.8 (3.9) | 0.174 |
| MMSE Score | 27.9 (2.4) | 27.7 (2.5) | 28.33 (1.5) | 0.330 |
| GM Volume (liter) | 0.602 (0.065) | 0.599 (0.066) | 0.617 (0.068) | 0.304 |
| WM Volume (liter) | 0.504 (0.061) | 0.495 (0.052) | 0.509 (0.065) | 0.243 |
| TIV (liter) | 1.379 (0.119) | 1.368 (0.113) | 1.394 (0.134) | 0.425 |
Data are presented as mean (standard deviation) and *number (percentage). P values were derived from analysis of variance. Abbreviations: MMSE, Minimental State Examination; GM, grey matter; WM, white matter; TIV, total intracranial volume; APOE, apolipoprotein E.