Fig. 1. (a) (Top) Scheme illustrating the photorelease reaction of the AQ photocage upon irradiation in CH2Cl2 or H2O with red light and (bottom) structures of conjugates 1–4. Hashed lines indicate bonds that break upon irradiation. (b) Changes in absorption of 1 dissolved in CH2Cl2 (0.34 mM, 0.5 mL) upon red light irradiation (λex > 590 nm, 183 mW, 65 mW cm–2); red light absorption is shaded in red. Inset: photograph of the color change before (purple) and after irradiation (yellow). (c) Kinetics of the photoreaction of 1 dissolved in H2O (5% CH3CN, 0.34 mM, 0.5 mL) and 1–4 dissolved in CH2Cl2 (0.34 mM, 0.5 mL). Reaction progression = (1 – A/A0) × 100%, where A = absorbance at 535 nm.
