Table 4.
Incidence of chronic graft vs host disease (cGvHD) overall, cGvHD of the lung, treatment related mortality (TRM), and overall survival (OS) in patients with a decline of FEV1 from day +90 to day +180 or to day +365, or from day +180 to day +365, of more than 10% compared to patients with no change or a decrease of less than 10%
| Time period | FEV1 decline >10% | cGvHD % (n) | cGvHD lung % (n) | TRM % (n) | OS % (n) |
|---|---|---|---|---|---|
| Day +90 – day +180 |
no |
59.5 (44) |
16.2 (12) |
12.2 (9) |
64.9 (48) |
| yes |
47.4 (9) |
15.8 (3) |
10.5 (2) |
73.7 (14) |
|
| Day +90 – day +365 |
no |
56.3 (36) |
9.4 (6) |
6.3 (4) |
84.4 (54) |
| yes |
65.2 (15) |
26.1 (6) |
8.7 (2) |
78.3 (18) |
|
| Day +180 – day +365 | no |
53.4 (39) |
11.0 (8) |
5.5 (1) |
82.2 (60) |
| yes | 93.8 (15) | 56.3 (9) | 25.0 (4) | 56.3 (9) |