Table 3. MLST Data of Tigecycline Nonsusceptible K. pneumoniae Isolates.
| Isolate ID | Allele types | CTX-M | tet | ramR mutation | ST | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| gapA | infB | mdh | pgi | phoE | rpoB | tonB | |||||
| 2 | 4 | 3 | 1 | 36 | 9 | 10 | 14 | (-) | (-) | (-) | 661 |
| 3 | 2 | 1 | 1 | 1 | 9 | 4 | 12 | (-) | (-) | (-) | 23 |
| 4 | 2 | 1 | 2 | 1 | 10 | 4 | 13 | (-) | (-) | (+) | 65 |
| 5 | 2 | 9 | 2 | 1 | 13 | 1 | 16 | (-) | (-) | (-) | 37 |
| 7 | 2 | 3 | 1 | 1 | 4 | 4 | 4 | CTX-M-15 | tetA | (-) | 20 |
| 8 | 3 | 3 | 1 | 1 | 1 | 1 | 4 | (-) | tetA | (-) | 11 |
| 9 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | (-) | tetA | (+) | 15 |
| 10 | 2 | 10 | 1 | 1 | 14 | 3 | 20 | (-) | (-) | (-) | 6 |
| 11 | 25 | 10 | 1 | 1 | 20 | 1 | 22 | CTX-M-15 | (-) | (+) | 789 |
| 13 | 2 | 1 | 1 | 1 | 9 | 4 | 12 | (-) | (-) | (-) | 23 |
| 14 | 3 | 3 | 1 | 1 | 1 | 1 | 4 | (-) | tetA | (+) | 11 |
| 15 | 2 | 1 | 2 | 1 | 7 | 1 | 81 | (-) | (-) | (-) | 268 |
| 16 | 4 | 1 | 2 | 52 | 1 | 1 | 7 | (-) | (-) | (+) | 307 |
| 17 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | CTX-M-15 | (-) | (+) | 15 |
| 18 | 32 | 1 | 1 | 1 | 9 | 4 | 12 | (-) | (-) | (-) | 1637 |
| 19 | 3 | 3 | 1 | 1 | 1 | 1 | 4 | (-) | (-) | (-) | 11 |
| 20 | 2 | 1 | 2 | 1 | 7 | 1 | 14 | (-) | (-) | (+) | 564 |
| 21 | 3 | 3 | 1 | 1 | 1 | 1 | 4 | (-) | (-) | (+) | 11 |
| 22 | 3 | 4 | 6 | 1 | 7 | 4 | 38 | (-) | (-) | (-) | 147 |
| 23 | 25 | 10 | 1 | 1 | 20 | 1 | 22 | CTX-M-15 | (-) | (-) | 789 |
| 24 | 98 | 75 | 18 | 89 | 11 | 41 | 194 | (-) | (-) | (-) | 1638 |
| 25 | 25 | 10 | 1 | 1 | 20 | 1 | 22 | CTX-M-15 | (-) | (+) | 789 |
| 26 | 25 | 10 | 1 | 1 | 20 | 1 | 22 | CTX-M-15 | (-) | (-) | 789 |
| 27 | 25 | 10 | 1 | 1 | 20 | 1 | 22 | (-) | (-) | (-) | 789 |
| 28 | 25 | 10 | 1 | 1 | 20 | 1 | 22 | CTX-M-15 | (-) | (-) | 789 |
| 29 | 25 | 10 | 1 | 1 | 20 | 1 | 22 | CTX-M-15 | (-) | (-) | 789 |
| 30 | 3 | 3 | 1 | 1 | 1 | 1 | 4 | (-) | (-) | (+) | 11 |
| 31 | 58 | 24 | 43 | 40 | 106 | 29 | 67 | (-) | tetA | (+) | 581 |
| 32 | 2 | 9 | 2 | 1 | 13 | 1 | 16 | (-) | tetA | (+) | 37 |
| 33 | 3 | 3 | 1 | 1 | 1 | 1 | 4 | CTX-M-15 | (-) | (+) | 11 |
| 34 | 3 | 3 | 1 | 1 | 1 | 1 | 4 | CTX-M-3 | (-) | (+) | 11 |
| 35 | 2 | 5 | 2 | 2 | 7 | 1 | 10 | CTX-M-15 | tetA | (-) | 48 |
| 36 | 3 | 4 | 6 | 1 | 7 | 4 | 4 | CTX-M-15 | tetA | (+) | 273 |
| 37 | 2 | 5 | 2 | 2 | 7 | 1 | 10 | CTX-M-15 | tetA | (-) | 48 |
| 38 | 4 | 51 | 2 | 1 | 12 | 4 | 42 | CTX-M-15 | tetA | (+) | 1639 |
| 41 | 3 | 3 | 1 | 1 | 1 | 1 | 4 | (-) | (-) | (-) | 11 |
| 42 | 43 | 1 | 2 | 1 | 10 | 4 | 13 | (-) | (-) | (+) | 375 |
| 43 | 9 | 4 | 2 | 1 | 1 | 1 | 27 | (-) | (-) | (-) | 86 |
| 44 | 4 | 1 | 2 | 52 | 1 | 1 | 7 | (-) | tetA | (+) | 307 |
| 45 | 2 | 1 | 2 | 1 | 7 | 1 | 7 | (-) | tetA | (+) | 36 |
| 46 | 4 | 1 | 1 | 1 | 9 | 4 | 12 | (-) | (-) | (+) | 793 |
| 47 | 4 | 1 | 2 | 52 | 1 | 1 | 7 | (-) | tetA | (+) | 307 |
| 48 | 3 | 3 | 1 | 1 | 1 | 1 | 23 | (-) | (-) | (+) | 270 |
| 49 | 2 | 1 | 2 | 1 | 7 | 1 | 81 | (-) | tetA | (-) | 268 |
| 50 | 4 | 4 | 1 | 1 | 7 | 4 | 10 | (-) | (-) | (-) | 1 |
| 51 | 2 | 1 | 2 | 1 | 10 | 4 | 46 | (-) | (-) | (-) | 280 |
| 52 | 3 | 3 | 1 | 1 | 1 | 1 | 4 | (-) | tetA | (-) | 11 |
| 53 | 2 | 1 | 2 | 1 | 10 | 1 | 57 | (-) | (-) | (-) | 835 |
| 54 | 4 | 1 | 2 | 52 | 1 | 1 | 7 | CTX-M-15 | tetA | (+) | 307 |
| 55 | 2 | 1 | 1 | 1 | 9 | 4 | 12 | (-) | (-) | (-) | 23 |
| 56 | 2 | 5 | 1 | 1 | 9 | 1 | 6 | (-) | (-) | (+) | 252 |
| 57 | 2 | 5 | 2 | 2 | 7 | 1 | 10 | CTX-M-15 | tetA | (-) | 48 |
| 58 | 3 | 4 | 6 | 1 | 7 | 4 | 4 | CTX-M-15 | (-) | (+) | 273 |
| 59 | 3 | 3 | 1 | 1 | 1 | 1 | 4 | (-) | (-) | (+) | 11 |
| 60 | 2 | 1 | 1 | 1 | 4 | 27 | 12 | CTX-M-14 | tetA | (-) | 261 |
| 62 | 3 | 3 | 1 | 1 | 1 | 1 | 4 | (-) | (-) | (-) | 11 |
MLST, multilocus sequence typing.