Fig. 2. Effects of OSM and ERK inhibitor (U0126) on protein expression of total and phosphorylated ERK. ERK phosphorylation in HTR8/SVneo cells was transiently stimulated by OSM (A). The effect of OSM on ERK phosphorylation was inhibited by pretreatment with U0126 (10 or 25 µM for 1 h) compared to OSM treatment alone (B). The expression was quantified and expressed as mean±SEM (C) compared to the control, *p<0.05. OSM, oncostatin M; ERK, extracellular signal-regulated kinase.
