Table 3. In vivo dynamics of LF/EF ratio in plasma and ear cutaneous tissue during infection with B. anthracis.
| Infection with | Sample | LF/EF ratio at each stage of infection stratified along the bioluminescence signal |
||||
|---|---|---|---|---|---|---|
| I | II | III | IV | V | ||
| 9602WT-lux | Ear cutaneous tissue | 5.51 ± 0.22 (5) | 3.15 ± 0.13 (14) | 2.77 ± 0.17 (8) | 2.61 ± 0.2 (4) | 2.95 ± 0.29 (6) |
| Plasma | 3.17 ± 0.31 (5) | 2.69 ± 0.28 (5) | 1.91 ± 0.28 (12) | 0.49 ± 0.37 (7) | 1.7 ± 0.45 (6) | |
| 9602P (ΔpagA)-lux | Ear cutaneous tissue | 4.17 ± 0.38 (3) | 3.49 ± 0.13 (7) | 2.17 ± 0.4 (12) | 1.49 ± 0.74 (4) | 2.28 ± 0.94 (5) |
| Plasma | 2.73 ± 0.13 (19) | 2.04 ± 0.25 (7) | 1.68 ± 0.24 (10) | 1.7 ± 0.34 (4) | 1.68 ± 0.04 (4) | |
The LF/EF ratio was calculated for each individual mouse displaying values over the thresholds for both LF and EF in the ear cutaneous tissue and the plasma. Data are expressed as mean log10 ± SEM, number of samples (n) in brackets. Same experimental conditions as in Table 2.