[Table/Fig-1]:
Factors for SIL cases & control subjects.
| Variable | Controls | SIL | p value |
|---|---|---|---|
| N (number) | 31 | 31 | - |
| Mean age (SD) years | 33.25 (± 6.96) | 35.16 (±7.09) | 0.29 |
| Parity (SD) | 2.35 (0.83) | 2.45 (0.80) | 0.64 |
| N Tobacco users*(%) | 6 (19.35%) | 5 (16.12) | 0.74 |
| Mean IGF-I (SD) ng/ml | 147.03 (± 62.65) | 202.8 (± 64.37) | 0.001 |
| Mean IGF-II (SD) ng/ml | 604.03 (± 104.31) | 781.22 (± 167.48) | <0.001 |
| Mean IGFBP-3 (SD) ng/ml | 2818.5 (± 666.68) | 2867.41 (± 703.11) | 0.89 |
| Mean C-Peptide (SD) ng/ml | 5.31 (± 2.14) | 4.23 (± 1.96) | 0.04 |
| BMI (SD) kg/m2 | 20.24 (±3.45) | 20.65 (±3.28) | 0.63 |
| MR-1 (95% CI)† | 0.19 (0.16-0.22) | 0.27 (0.23-0.31) | 0.001 |
| MR-2 (95% CI)‡ | 0.85 (0.77-0.92) | 1.08 (0.98-1.17) | <0.001 |
| CMR (95% CI)§ | 1.04 (0.96-1.12) | 1.35 (1.23-1.47) | <0.001 |
| BEMR (95% CI) Π | 0.11 (0.08-0.12) | 0.29 (0.16-0.42) | <0.001 |
*Smoking/Chewing †MR-1 = 3.72 x IGF-I/IGFBP-3 ‡MR-2 = 3.82 x IGF-II/IGFBP-3 §CMR = 3.72 x (IGF-I + 1.02 x IGF-II)/IGFBP-3. Π BEMR = 3.72 x {(0.25 x IGF-I) + (0.032 x IGF-II) + (0.0025 x C-peptide)} / {(1435 + IGFBP-3) – (2.79 x IGF-I) – (2.87 x IGF-II)}.