Skip to main content
. Author manuscript; available in PMC: 2017 Mar 15.
Published in final edited form as: Circulation. 2016 Mar 15;133(11):1125–1130. doi: 10.1161/CIRCULATIONAHA.115.017787

Table 2.

Strategies to Prevent and/or Manage Perioperative Cardiovascular Events Under Investigation

Table 2. Prevention and Treatment Strategies Under Investigation
Prevention of Perioperative Cardiovascular Events:
High Intensity Statin Lowering the Risk of Operative Complications Using Atorvastatin Loading Dose (LOAD) (NCT01543555)
Ranolazine Pathophysiology and Prevention of Perioperative Myocardial Injury (NCT01810796)
Ischemic Preconditioning Preconditioning Shields Against Vascular Events in Surgery (SAVES) (NCT01691911)
Prevention of Myocardial Injury in Non-cardiac Surgery (PIXIE) (NCT02344797)
Combination Therapy (ACEi, Beta-Blocker, Statin) Optimization of Pre-surgical Testing With an Intensive Multifactorial Intervention to MinimiZe Cardiovascular Events in Orthopedic Surgery (NCT01837069)
Post-operative Management of Perioperative Cardiovascular Events
Ticagrelor Study of Ticagrelor Versus Aspirin Treatment in Patients With Myocardial Injury Post Major Non-cardiac Surgery (INTREPID) (NCT02291419)
Dabigatran Management of Myocardial Injury After Noncardiac Surgery Trial (MANAGE) (NCT01661101)

Abbreviations: ACEi: Angiotensin-converting-enzyme inhibitor