Figure 2.

Recursive partitioning for TTT. (A). A recursive partitioning algorithm used GEP and clinical variables to define distinct clinically relevant risk groups. (B). A high-risk group is defined by GEP4 ≥9.28 and has a 2-year progression probability of 85.7%; a low-risk group comprises patients with GEP4 <9.28, M-protein <3 g/dL and albumin ≥3.5 g/dL and has a 5% probability of progression at 2 years; and an intermediate-risk group featured patients not in the high-risk or low-risk group and has a 2-year progression probability of 44.8%, UAMS: University of Arkansas for Medical Sciences.