Figure 2.
Overall survival by base-line covariates.a Patients were required to have platelet counts (PLT) ≥ 100×109/L at baseline. bAdjusted for prognostic base-line characteristics and controlled for treatment. Hazard ratio (HR) > 1 indicates an increased risk of death. Higher Hb level, secondary MF subtype, female sex, and higher platelet count were associated with better prognosis while higher base-line WBC, age, and spleen volume were associated with worse prognosis independently of treatment. For the following continuous covariates the risk of death was incrementally lower on each unit increase (Hb, platelet count) or incrementally higher (WBC, age, and spleen volume). Hb: hemoglobin; MF: myelofibrosis; PET: post–essential thrombocythemia; PPV: post–polycythemia vera; WBC: white blood cell count.