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. Author manuscript; available in PMC: 2016 Mar 21.
Published in final edited form as: Exp Neurol. 2014 Dec 2;264:135–149. doi: 10.1016/j.expneurol.2014.11.009

Figure 6. Comparison of the response of sham and X-irradiated mice to KA without pretreatment with ethosuximide.

Figure 6

A. The experimental timeline is shown for treatment of Sham- and X-irradiated mice with 16 mg/kg KA (n = 10/group).

B. Example of the response to KA in a Sham-treated and X-irradiated mouse.

C. 1–2. There were no significant differences in the latency to the first seizure. 3. There no significant differences in the numbers of seizures. 4. The total duration of convulsive seizures was greater in X-irradiated mice compared to Sham-irradiated mice.

D. 1–3. There were no significant differences in IIS frequency between Sham-treated and X-irradiated mice 4–21 hrs after KA administration.