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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Anesth Analg. 2016 Apr;122(4):1081–1088. doi: 10.1213/ANE.0000000000001163

Table 1.

International Society for Heart and Lung Transplantation Primary Graft Dysfunction Definition and Grading.

Grade PaO2/FiO2 Radiographic Infiltrates
0 > 300 Absent
1 > 300 Present
2 200–300 Present
3 < 200 Present
PaO2/FiO2 = arterial oxygen partial pressure/fraction of inspired oxygen
  • Presence of extracorporeal life support post lung transplantation is considered grade-3
  • FiO2 > 50% and use of inhaled nitric oxide or inhaled epoprostenol while on mechanical ventilation > 48 hours is considered grade-3.
  • Any patient who is extubated on nasal cannula with FiO2 < 30% are graded as 0 or 1 depending on chest radiograph findings.
  • Absence of infiltrates on chest radiograph is graded as 0 even if PaO2/FiO2 ratio < 300