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. Author manuscript; available in PMC: 2016 Mar 21.
Published in final edited form as: Semin Reprod Med. 2014 Apr 8;32(3):159–165. doi: 10.1055/s-0034-1371087

Table 1.

Reduced second to fourth digit (finger) ratio as a marker of androgen excess in utero in PCOS women. See references 16–19.

Author Participant PCOS
definition		 Findings
Cattrall 2005 70 PCOS
70 NL women		 NIH Reduced 2D:4D ratio in right hand of
PCOS vs. normal women
Lujan 2010 98 PCOS
51 NL women		 Rotterdam No difference 2D:4D ratio
2D:4D ratio positively correlates with hirsutism, free androgen index and ovarian volume
Lujan 2010 96 PCOS
48 NL women
50 men		 Rotterdam No difference 2D:4D ratio by computer analysis
2D:4D ratio positively correlates with hirsutism, testosterone and free androgen index
Palomba 2012 30 PCOS
545 NL
women		 Rotterdam
(All androgen excess)		 Increased 2D:4D ratio in 4–11 year old daughters of PCOS vs. normal mothers