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. Author manuscript; available in PMC: 2016 Mar 21.
Published in final edited form as: Nature. 2015 May 4;522(7556):368–372. doi: 10.1038/nature14352

Extended Data Figure 4. Comparison of NMR spectra of PLOR-generated and 71nt-CN samples in adenine-bound form.

Extended Data Figure 4

Superposition of the 1H13C-TROSY spectra of 71nt-CN with Lp1-CN (a), Lp2-CN (b), Lp1+2-CN (c), Lk2-CN (d), S1+Lk1-CN (e), and 4nt-CN (f). These results indicate that the RNAs synthesized by PLOR have the same fold as 71nt-CN generated using the traditional solution-based transcription method and are functional as evidenced by binding of the adenine ligand.