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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: J Mol Cell Cardiol. 2015 Oct 19;89(Pt B):287–296. doi: 10.1016/j.yjmcc.2015.10.018

Figure 4.

Figure 4

Cardiac morphology and proliferation activity in compound Apc and β-catenin (β-Cat) deletion hearts at E17.5. A, Gross and H&E morphology of individual hearts with left ventricular walls zoomed in the bottom row. Scale bars, 1 mm (white and red) and 100 μm (black). B, pH3S10 or Ki67 co-stained with Actinin and DAPI. C, Percentage of pH3S10 and Ki67 positive CMs in β-Cat and Apc compound cKO mice at E17.5. Data are presented as mean ± SD from 3 to 4 embryos in each genotype. * P<0.05 and ** P<0.01 indicate statistically significant difference between the groups (ANOVA).