Table 2. Thermodynamic parameters of quadruplex (^Q) and i-motif (ⁱ) formation^a.

Sequence	−ΔH° (kcal/mol)	−ΔS° (eu)	ΔG°37 (kcal/mol)	TM (°C)
CCCUCCCUUUUCCCUCCCi	33.6±3.7	109.9±12.1	+0.46±0.21	32.8
CCCUCCCUUUUCCCUCCCi	35.2±2.9	115.1±9.3	+0.46±0.26	33.0
AGGAGGAGGAGGAQ	87.3±11.3	233.4±32.8	−14.88±1.13	73.6
AGGAGGAGGAGGAQ	96.4±2.3	260.2±6.8	−15.71±0.21	73.0

a–solution: 100 mM KCl, 20mM sodium cacodylate, 0.5mM EDTANa₂, pH 7.0 (quadruplex) or 3.4 (i-motif),

italics– β-L-RNA.