. 2016 Feb 23;11(2):e0149478. doi: 10.1371/journal.pone.0149478

Table 3. Thermal stability of model heterochiral duplexes^a.

Name	Duplexes (5ʹ–3ʹ)		T_m^b (°C)	ΔT_m^b (°C)
D1	AGAAAGAGAAGA	UCUUUCUCUUCU	50.0	0
D2	AGAAAGAGAAGA	UCUUUCUCUUCU	15.9	−34.1
D3	AGAAAGAGAAGA	UCUUUCUCUUCU	17.9	−32.1
D4	AGAAAGAGAAGA	UC^LUUUC^LUCUUC^LU	63.6	0
D5	AGAAAGAGAAGA	UC^LUUUC^LUCUUC^LU	41.5	−22.1
D6	AGAAAGAGAAGA	U^MC^MU^MU^MU^MC^MU^MC^MU^MU^MC^MU^M	57.6	0
D7	AGAAAGAGAAGA	U^MC^MU^MU^MU^MC^MU^MC^MU^MU^MC^MU^M	26.1	−31.5
D8	A^MG^MA^MA^MA^MG^MA^MG^MA^MA^MG^MA^M	UCUUUCUCUUCU	52.0	0
D9	A^MG^MA^MA^MA^MG^MA^MG^MA^MA^MG^MA^M	UCUUUCUCUUCU	13.5	−38.5
D10	AGAAAGAGAAGA	U^MC^LU^MU^MU^MC^LU^MC^MU^MU^MC^LU^M	68.7	0
D11	AGAAAGAGAAGA	U^MC^LU^MU^MU^MC^LU^MC^MU^MU^MC^LU^M	47.7	−21.0

a–solution: 1 M NaCl, 20 mM sodium cacodylate, 0.5 mM Na₂EDTA, pH 7.0;

b–calculated for a 20 µM oligomer concentration;

2ʹ-OMe-RNAs are shown as A^M, C^M, G^M, U^M; LNA-C is shown as C^L, and the beta-L-oligomers are italicized.

Table 3. Thermal stability of model heterochiral duplexesa.